Journal article
Bis(1,3-dihydroxy-isopropyl)amine (BDI) as an AB(4) dendritic building block: rapid synthesis of a second generation dendrimer
- Abstract:
- Bis(1,3-dihydroxy-isopropyl)amine (BDI)1, a symmetrical AB4 dendritic building block, is developed into two diamine linkers in which the nitrogen is more nucleophilic. The four primary alcohols in BDI undergo Michael reactions with t-butyl acrylate. Branch cells of this rare multiplicity allow the rapid construction of a second generation dendrimer 5 with 48 protected peripheral primary alcohol groups. (C) 2000 Elsevier Science Ltd.
- Publication status:
- Published
Actions
Authors
- Journal:
- TETRAHEDRON LETTERS More from this journal
- Volume:
- 41
- Issue:
- 20
- Pages:
- 3959-3962
- Publication date:
- 2000-05-21
- DOI:
- ISSN:
-
0040-4039
- Language:
-
English
- Pubs id:
-
pubs:37384
- UUID:
-
uuid:f11b8bf7-902d-4360-9616-bcf5ff55477d
- Local pid:
-
pubs:37384
- Source identifiers:
-
37384
- Deposit date:
-
2012-12-19
Terms of use
- Copyright date:
- 2000
If you are the owner of this record, you can report an update to it here: Report update to this record