- Abstract:
-
Type III secretion systems are essential virulence determinants for many Gram-negative bacterial pathogens. The type III secretion system consists of cytoplasmic, transmembrane, and extracellular domains. The extracellular domain is a hollow needle protruding above the bacterial surface and is held within a basal body that traverses both bacterial membranes. Effector proteins are translocated, via this external needle, directly into host cells, where they subvert normal cell functions to aid ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1073/pnas.0602689103
-
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- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 103
- Issue:
- 33
- Pages:
- 12529-12533
- Publication date:
- 2006-08-05
- DOI:
- EISSN:
-
1091-6490
- ISSN:
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0027-8424
- URN:
-
uuid:f112ca37-6fdd-4e33-9f54-cf22354cecf7
- Source identifiers:
-
20454
- Local pid:
- pubs:20454
- Copyright date:
- 2006
Journal article
Molecular model of a type III secretion system needle: Implications for host-cell sensing.
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