Journal article
Cell proliferation is a key determinant of the outcome of FOXO3a activation.
- Abstract:
-
The FOXO family of forkhead transcription factors have a pivotal role in determining cell fate in response to oxidative stress. FOXO activity can either promote cell survival or induce cell death. Increased FOXO-mediated cell death has been implicated in the pathogenesis of degenerative diseases affecting musculoskeletal tissues. The aim of this study was to determine the conditions under which one member of the FOXO family, FOXO3a, promotes cell survival as opposed to cell death. Treatment o...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Biochemical and biophysical research communications More from this journal
- Volume:
- 462
- Issue:
- 1
- Pages:
- 78-84
- Publication date:
- 2015-06-01
- DOI:
- EISSN:
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1090-2104
- ISSN:
-
0006-291X
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:523239
- UUID:
-
uuid:f0fa8892-087d-483b-b15d-182bae1010b9
- Local pid:
-
pubs:523239
- Source identifiers:
-
523239
- Deposit date:
-
2016-07-21
Terms of use
- Copyright date:
- 2015
- Notes:
-
publisher: Elsevier
articletitle: Cell proliferation is a key determinant of the outcome of FOXO3a activation
journaltitle: Biochemical and Biophysical Research Communications
articlelink: http://dx.doi.org/10.1016/j.bbrc.2015.04.112
content_type: article
copyright: Copyright © 2015 The Authors. Published by Elsevier Inc.
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