- Abstract:
-
The earliest generated cells of the mammalian cerebral cortex form the preplate layer (PPL). The subsequently born cortical plate (CP) cells split this layer into the superficial layer I (LI) and the deep subplate (SP). The cellular and molecular mechanisms that underlie this event are unclear. To investigate the role of the cyclin-dependent kinase 5 (Cdk5) and its activator p35 in preplate splitting, we used Nissl staining, carbocyanine dye tracing, cell birthdating, and immunohistochemistry...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/cercor/bhj172
-
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- Volume:
- 16 Suppl 1
- Issue:
- SUPPL. 1
- Pages:
- i35-i45
- Publication date:
- 2006-07-05
- DOI:
- EISSN:
-
1460-2199
- ISSN:
-
1047-3211
- URN:
-
uuid:f0ed0bdb-7b8a-4f82-8da4-3e980eafb6ed
- Source identifiers:
-
114663
- Local pid:
- pubs:114663
- Copyright date:
- 2006
Conference
Role of p35/Cdk5 in preplate splitting in the developing cerebral cortex.
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