Journal article
Reconstitution of the core of the malaria parasite glideosome with recombinant Plasmodium class XIV myosin A and Plasmodium actin
- Abstract:
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Motility of the apicomplexan malaria parasite Plasmodium falciparum is enabled by a multiprotein glideosome complex, whose core is the class XIV myosin motor, PfMyoA, and a divergent Plasmodium actin (PfAct1). Parasite motility is necessary for host-cell invasion and virulence, but studying its molecular basis has been hampered by unavailability of sufficient amounts of PfMyoA. Here, we expressed milligram quantities of functional full-length PfMyoA with the baculovirus/Sf9 cell expression sy...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.2MB, Terms of use)
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- Publisher copy:
- 10.1074/jbc.M117.813972
Authors
Funding
Bibliographic Details
- Publisher:
- American Society for Biochemistry and Molecular Biology
- Journal:
- Journal of Biological Chemistry More from this journal
- Volume:
- 292
- Pages:
- 19290-19303
- Publication date:
- 2017-10-04
- Acceptance date:
- 2017-09-27
- DOI:
- EISSN:
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1083-351X
- ISSN:
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0021-9258
- Pmid:
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28978649
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:965757
- UUID:
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uuid:f0e86d37-af8e-431a-95e5-8645212a766e
- Local pid:
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pubs:965757
- Source identifiers:
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965757
- Deposit date:
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2019-01-28
Terms of use
- Copyright holder:
- American Society for Biochemistry and Molecular Biology
- Copyright date:
- 2017
- Notes:
-
© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.
Final version free via Creative Commons CC-BY license.
- Licence:
- CC Attribution (CC BY)
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