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Journal article

Expanding the use of primaquine for the radical cure of Plasmodium vivax

Abstract:
There is currently strong impetus for global malaria eradication with many National Malaria Control Programs setting ambitious elimination targets. Whilst intensified malaria control efforts have reduced the burden of falciparum malaria significantly, the fragile gains made thus far remain vulnerable to the threat of emergence and spread of multidrug resistant parasites. Outside of Sub-Saharan Africa, the decline in falciparum malaria has also been shadowed by a rise in the proportion of malaria due to P. vivax, which is now the predominant cause of malaria in these regions. Vivax malaria is more difficult to eradicate than P. falciparum because it can form dormant liver stages (hypnozoites) that reactivate periodically, causing recurrent infections (relapses) and further transmission.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/cid/ciy236

Authors

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
ORCID:
0000-0003-2000-2874


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Grant:
Senior Research Fellowship


Publisher:
Oxford University Press
Journal:
Clinical Infectious Diseases More from this journal
Volume:
67
Issue:
7
Pages:
1008–1009
Publication date:
2018-03-24
Acceptance date:
2018-03-24
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Pmid:
29590343


Language:
English
Keywords:
Pubs id:
pubs:834097
UUID:
uuid:f0e6861b-1aa0-4ee6-b2dc-00a8b10f3e47
Local pid:
pubs:834097
Source identifiers:
834097
Deposit date:
2018-04-11
ARK identifier:

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