Journal article
A modular synthesis of conformationally preorganised extended β-strand peptidomimetics
- Abstract:
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A promising strategy for mediating protein-protein interactions is the use of non-peptidic mimics of secondary structural protein elements, such as the α-helix. Recent work has expanded the scope of this approach by providing proof-of-principle scaffolds that are conformationally biased to mimic the projection of side-chains from one face of another common secondary structural element-the β-strand. Herein, we present a synthetic route that has key advantages over previous work: monomers beari...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Preview, Accepted manuscript, pdf, 3.6MB, Terms of use)
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- Publisher copy:
- 10.1002/chem.201501366
Authors
Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Chemistry - A European Journal More from this journal
- Volume:
- 21
- Issue:
- 42
- Pages:
- 14699-14702
- Publication date:
- 2015-08-17
- Acceptance date:
- 2015-08-17
- DOI:
- EISSN:
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1521-3765
- ISSN:
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0947-6539
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:567674
- UUID:
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uuid:f0bdec64-6f4f-4eca-839b-7bb8cc2ed93c
- Local pid:
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pubs:567674
- Source identifiers:
-
567674
- Deposit date:
-
2016-03-30
Terms of use
- Copyright holder:
- WILEY-VCH Verlag
- Copyright date:
- 2015
- Notes:
- © 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim. This is the accepted manuscript version of the article. The final version is available online from Wiley at: [10.1002/chem.201501366]
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