Journal article

Regulatory T cells in transplantation tolerance.

Abstract:: Our ability to harness tolerance mechanisms will have a major impact in organ transplantation if it becomes possible to minimize drug maintenance, or even wean off immunosuppressive drugs. An improved understanding of the biology of regulatory T cells will make it possible to replace current induction regimens with those favouring the vaccination and selection of T cells that prevent graft rejection. Once tolerance is established, the continuous supply of graft antigens should sustain T cell mediated regulation as the dominant mechanism preventing graft rejection.

Publication status:: Published

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APA Style

Waldmann, H., Graca, L., Adams, E., Fairchild, P., & Cobbold, S. (2005). Regulatory T cells in transplantation tolerance. Current Topics in Microbiology and Immunology, 293, 249–264.

MLA Style

Waldmann, H., et al. “Regulatory T Cells in Transplantation Tolerance.” Current Topics in Microbiology and Immunology, vol. 293, 2005, pp. 249–64.

Chicago Style

Waldmann, H, L Graca, E Adams, P Fairchild, and S Cobbold. 2005. “Regulatory T Cells in Transplantation Tolerance.” Current Topics in Microbiology and Immunology 293: 249–64.
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Publisher copy:: 10.1007/3-540-27702-1_11

Authors

+ Waldmann, H More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Pathology Dunn School
Role:: Author

+ Graca, L More by this author

Role:: Author

+ Adams, E More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Pathology Dunn School
Role:: Author

+ Fairchild, P More by this author

Role:: Author

+ Cobbold, S More by this author

Role:: Author

Journal:: Current topics in microbiology and immunology More from this journal
Volume:: 293
Pages:: 249-264
Publication date:: 2005-01-01
DOI:: 10.1007/3-540-27702-1_11
ISSN:: 0070-217X

Language:: English
Keywords:: Humans

Immunophenotyping

Animals

Graft Rejection

Transplantation Tolerance

Tissue Donors

T-Lymphocytes

Antigens

Immunosuppression
Pubs id:: pubs:20450
UUID:: uuid:f0b94834-c100-47d3-936b-cea99884f359
Local pid:: pubs:20450
Source identifiers:: 20450
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2005

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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