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Investigation into the neural correlates of emotional augmentation of clinical pain

Abstract:

Although depressive mood is an important psychological determinate of chronic pain, the neural circuitry that mediates its influence on the pain experience is largely unknown. We used functional magnetic resonance imaging (FMRI) to investigate the neurophysiological interactions between depressive symptoms and disease-relevant pain in rheumatoid arthritis (RA) patients. RA is associated with chronic joint pain and swelling, but peripheral joint pathology often does not fully explain the amoun...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.neuroimage.2007.12.016

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Centre for Functional Magnetic Resonance Imaging
Role:
Author
More by this author
Institution:
University of Oxford
Research group:
Centre for Functional Magnetic Resonance Imaging
Department:
Medical Sciences Division - Clinical Neurology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Centre for Functional Magnetic Resonance Imaging
Role:
Author
More by this author
Institution:
N & GI CEDD, Glaxo Smith Kline, Harlow, UK
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Elsevier
Journal:
NeuroImage More from this journal
Volume:
40
Issue:
2
Pages:
759-766
Publication date:
2008-04-01
DOI:
ISSN:
10538119
Language:
English
Keywords:
Subjects:
UUID:
uuid:f0a23f9a-dcb7-40c3-9700-718e706c64aa
Local pid:
ora:5374
Deposit date:
2011-05-26

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