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Substituted epoxides by lithiation of terminal epoxides.

Abstract:
Diamine-ligand-assisted direct hydrogen-lithium exchange allows the generation of nonstabilized (H-substituted) oxiranyllithium species and their subsequent trapping by Bu(3)SnCl and carbonyl-based electrophiles. This reaction provides a new concise route to alpha,beta-epoxystannanes and substituted epoxides.
Publication status:
Published

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Publisher copy:
10.1021/ol048544j

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Organic letters More from this journal
Volume:
6
Issue:
23
Pages:
4187-4189
Publication date:
2004-11-01
DOI:
EISSN:
1523-7052
ISSN:
1523-7060


Language:
English
Pubs id:
pubs:32897
UUID:
uuid:f09d53d9-df3e-4934-a49d-003f1d5c8a57
Local pid:
pubs:32897
Source identifiers:
32897
Deposit date:
2012-12-19
ARK identifier:

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