Anti-cell surface endothelial antibodies in sera from cardiac and kidney transplant recipients: association with chronic rejection.

Journal article

The aetiologies of accelerated or transplant-associated coronary artery disease (TxCAD) following cardiac transplantation and chronic rejection following renal transplantation remain ill-defined. Previous studies have used Western blotting to demonstrate an association between the formation of anti-endothelial (anti-EC) antibodies and TxCAD after heart transplantation. However, Western blotting favours detection of cytosolic proteins. The objectives of this study were to determine whether flo...

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Authors: Ferry, B; Welsh, K; Dunn, M; Law, D; Proctor, J

• Publication status: Published
• Journal: Transplant immunology
• Volume: 5
• Issue: 1
• Pages: 17-24
• Publication date: 1997-03-01
• DOI: 10.1016/s0966-3274(97)80021-4
• EISSN: 1878-5492
• ISSN: 0966-3274
• Language: English
• Keywords: Endothelium, Vascular; Adult; Kidney Transplantation; Cells, Cultured; Male; Graft Rejection; Autoantibodies; Child; Antibodies, Antineutrophil Cytoplasmic; Heart Transplantation; Female; Adolescent; Isoantibodies; Middle Aged; Antigens, Surface; Coronary Artery Disease; Immunoglobulin G; Humans; Immunoglobulin M