Effect of immigration on multiple sclerosis sex ratio in Canada: the Canadian Collaborative Study.

Journal article

BACKGROUND: The ratio of female to male (F:M) multiple sclerosis (MS) cases varies geographically, generally being greater in areas of high prevalence. In many regions, including Canada, rising MS incidence in women has been implied by the marked increase in F:M ratio. METHODS: We examined the F:M ratio over time in MS patients in the Canadian Collaborative Study born outside Canada, with onset postmigration (n = 2531). We compared the trends to native-born Canadians, by region of origin and...

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Authors: Orton, S; Ramagopalan, S; Brocklebank, D; Herrera, B; Dyment, D

• Publication status: Published
• Journal: Journal of neurology, neurosurgery, and psychiatry
• Volume: 81
• Issue: 1
• Pages: 31-36
• Publication date: 2010-01-01
• DOI: 10.1136/jnnp.2008.162784
• EISSN: 1468-330X
• ISSN: 0022-3050
• Language: English
• Keywords: Humans; Prevalence; Adult; Multiple Sclerosis; Sex Ratio; Male; Canada; Time Factors; Age of Onset; Emigration and Immigration; Sex Factors; Age Factors; Female; Regression Analysis