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Journal article

Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse.

Abstract:

Regulation between the fed and fasted states in mammals is partially controlled by peroxisome proliferator-activated receptor-alpha (PPAR-alpha). Expression of the receptor is high in the liver, heart and skeletal muscle, but decreases with age. A combined (1)H nuclear magnetic resonance (NMR) spectroscopy and gas chromatography-mass spectrometry metabolomic approach has been used to examine metabolism in the liver, heart, skeletal muscle and adipose tissue in PPAR-alpha-null mice and wild-ty...

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Publication status:
Published

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Publisher copy:
10.1038/msb.2009.18

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Journal:
Molecular systems biology
Volume:
5
Pages:
259
Publication date:
2009-01-01
DOI:
EISSN:
1744-4292
ISSN:
1744-4292
URN:
uuid:f03bc1b6-1bc6-41b2-984d-ef99fe5f9286
Source identifiers:
106841
Local pid:
pubs:106841

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