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Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction.

Abstract:

Ionotropic glutamate receptors (iGluRs) are a highly conserved family of ligand-gated ion channels present in animals, plants, and bacteria, which are best characterized for their roles in synaptic communication in vertebrate nervous systems. A variant subfamily of iGluRs, the Ionotropic Receptors (IRs), was recently identified as a new class of olfactory receptors in the fruit fly, Drosophila melanogaster, hinting at a broader function of this ion channel family in detection of environmental...

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Authors


Cummins, SF More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Journal:
PLoS Genet
Volume:
6
Issue:
8
Pages:
e1001064
Publication date:
2010-08-05
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
URN:
uuid:f0132537-a1e6-457e-b7b9-861402943faf
Source identifiers:
345803
Local pid:
pubs:345803

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