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Regional differences in neurovascular coupling in rat brain as determined by fMRI and electrophysiology.

Abstract:

Increases in neuronal activity induce local increases in cerebral perfusion. However, our understanding of the processes underlying this neurovascular coupling remains incomplete and, particularly, how these vary across the brain. Recent work supports an important role for astrocytes in neurovascular coupling, in large part via activation of their metabotropic glutamate receptors (mGluR). Here, using a combination of functional magnetic resonance imaging (fMRI) and electrophysiology we demons...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
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Journal:
NeuroImage
Volume:
53
Issue:
2
Pages:
399-411
Publication date:
2010-11-01
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
Source identifiers:
113395

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