- Abstract:
- A stochastic sensing method: Discrimination between enantiomeric amino acids is achieved when the amino acids bind to a CuII complex within a protein nanopore sensor, which provides a chiral environment. The potential of the method is demonstrated by real-time observation of the increase in enantiomeric excess during an enzymatic kinetic resolution. Copyright © 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
- Publication status:
- Published
- Publisher copy:
- 10.1002/anie.201205687
-
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- Journal:
- Angewandte Chemie (International ed. in English)
- Volume:
- 51
- Issue:
- 38
- Pages:
- 9606-9609
- Publication date:
- 2012-09-05
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851
- URN:
-
uuid:efd6b4ab-b283-472e-8540-1999826e3ed9
- Source identifiers:
-
349796
- Local pid:
- pubs:349796
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Continuous stochastic detection of amino acid enantiomers with a protein nanopore.
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