Journal article

Influenza virus-specific cytotoxic T lymphocytes recognize HLA molecules. Blocking by monoclonal anti-HLA antibodies

Abstract:: The effect of monoclonal anti-HLA antibodies on lysis of influenza virus-infected target cells by sensitized cytotoxic T lymphocytes was measured. Lysis was blocked, provided the antibody was present in a concentration sufficient to saturate the HLA determinants on the target cells. Antibodies to monomorphic HLA determinants and to β2-microglobulin inhibited. Antibody to HLA A2 and B17 blocked lysis of target cells that shared these antigens with the effector cell. It was concluded that the restriction elements for influenza virus-specific cytotoxic T cells are the HLA molecules themselves.

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APA Style

Mcmichael, A., Parham, P., Brodsky, F., & Pilch, J. R. (1980). Influenza virus-specific cytotoxic T lymphocytes recognize HLA molecules. Blocking by monoclonal anti-HLA antibodies. Journal of Experimental Medicine, 152(2 II), 195–203.

MLA Style

Mcmichael, A, et al. “Influenza Virus-Specific Cytotoxic T Lymphocytes Recognize HLA Molecules. Blocking by Monoclonal Anti-HLA Antibodies.” Journal of Experimental Medicine, vol. 152, no. 2 II, 1980, pp. 195–203.

Chicago Style

Mcmichael, A, P Parham, F Brodsky, and JR Pilch. 1980. “Influenza Virus-Specific Cytotoxic T Lymphocytes Recognize HLA Molecules. Blocking by Monoclonal Anti-HLA Antibodies.” Journal of Experimental Medicine 152 (2 II): 195–203.
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Authors

+ Mcmichael, A More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: NDM Experimental Medicine
Role:: Author

+ Parham, P More by this author

Role:: Author

+ Brodsky, F More by this author

Role:: Author

+ Pilch, JR More by this author

Role:: Author

Journal:: Journal of Experimental Medicine More from this journal
Volume:: 152
Issue:: 2 II
Pages:: 195-203
Publication date:: 1980-01-01
ISSN:: 0022-1007

Language:: English
Pubs id:: pubs:94236
UUID:: uuid:ef9fcbf2-6f4e-453a-bcd3-4c402003b062
Local pid:: pubs:94236
Source identifiers:: 94236
Deposit date:: 2013-02-20
ARK identifier:: ark:/29072/ora_ef9fcbf26f4e453abcd34c402003b062

Terms of use

Copyright date:: 1980

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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