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Journal article

Economic evaluation plan of a RCT of hydroxyapatite-coated uncemented hemiarthroplasty versus cemented hemiarthroplasty for the treatment of displaced intracapsular hip fractures: the WHiTE5 trial

Abstract:

Aim

This paper describes the methods applied to assess the cost-effectiveness of cemented versus uncemented hemiarthroplasty among hip fracture patients in the World Hip Trauma Evaluation Five (WHiTE5) trial.

Methods

A within-trial cost-utility analysis (CUA) will be conducted at four months postinjury from a health system (National Health Service and personal social services) perspective. Resource use pertaining to healthcare utilization (i.e. inpatient care, physiotherapy, social care, and home adaptations), and utility measures (quality-adjusted life years) will be collected at one and four months (primary outcome endpoint) postinjury; only treatment of complications will be captured at 12 months. Sensitivity analysis will be conducted to assess the robustness of the results.

Conclusion

The planned analysis strategy described here records our intent to conduct a within-trial CUA alongside the WHiTE5 trial.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1302/2633-1462.13.bjo-2020-0003

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0001-5876-9363
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-8857-5743


Publisher:
British Editorial Society of Bone and Joint Surgery
Journal:
Bone and Joint Open More from this journal
Volume:
1
Issue:
3
Pages:
8-13
Publication date:
2020-03-01
Acceptance date:
2020-01-31
DOI:
EISSN:
2633-1462


Language:
English
Keywords:
Pubs id:
1084197
Local pid:
pubs:1084197
Deposit date:
2020-01-31

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