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Journal article

Genetic factors as determinants of infectious disease transmission in human communities.

Abstract:

Genetic factors may play an important role in individual susceptibility to infection. Hitherto this problem has been investigated by attempting to relate the distribution of genetic polymorphisms in populations to present or past infection, or by analysing specific infections by classical twin studies or group comparisons. There is reasonable evidence that the common red-cell polymorphisms involving haemoglobin, enzymes or membrane have been maintained by relative resistance to malaria. Blood...

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Publication status:
Published

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Publisher copy:
10.1098/rstb.1988.0095

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, Biomedical Research Centre
Role:
Author
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Journal:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Volume:
321
Issue:
1207
Pages:
327-348
Publication date:
1988-10-05
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
URN:
uuid:ef7d31a1-5aa5-46a6-ae88-c3d526e6a8b9
Source identifiers:
35267
Local pid:
pubs:35267

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