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Conformational spread in the flagellar motor switch: a model study

Abstract:

The reliable response to weak biological signals requires that they be amplified with fidelity. In E. coli, the flagellar motors that control swimming can switch direction in response to very small changes in the concentration of the signaling protein CheY-P, but how this works is not well understood. A recently proposed allosteric model based on cooperative conformational spread in a ring of identical protomers seems promising as it is able to qualitatively reproduce switching, locked state ...

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Publication date:
2012-01-01
URN:
uuid:ef741e9f-d1b8-4f1d-aa0e-5d1e59c77ef9
Local pid:
oai:eprints.maths.ox.ac.uk:1517

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