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Journal article

The interleukin-23 axis in intestinal inflammation.

Abstract:

Immune responses in the intestine are tightly regulated to ensure host protective immunity in the absence of immune pathology. Interleukin-23 (IL-23) has recently been shown to be a key player in influencing the balance between tolerance and immunity in the intestine. Production of IL-23 is enriched within the intestine and has been shown to orchestrate T-cell-dependent and T-cell-independent pathways of intestinal inflammation through effects on T-helper 1 (Th1) and Th17-associated cytokines...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Immunological reviews
Volume:
226
Issue:
1
Pages:
147-159
Publication date:
2008-12-05
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
URN:
uuid:ef71f954-a7c7-45af-82d2-ab4d1f0b2018
Source identifiers:
19732
Local pid:
pubs:19732

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