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Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones.

Abstract:

This study describes the pattern and extent of drug resistance in 1,774 strains of Salmonella enterica serovar Typhi isolated across Asia between 1993 and 2005 and characterizes the molecular mechanisms underlying the reduced susceptibilities to fluoroquinolones of these strains. For 1,393 serovar Typhi strains collected in southern Vietnam, the proportion of multidrug resistance has remained high since 1993 (50% in 2004) and there was a dramatic increase in nalidixic acid resistance between ...

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Publication status:
Published

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Publisher copy:
10.1128/aac.00294-07

Authors


Campbell, JI More by this author
Galindo, CM More by this author
Van Minh Hoang, N More by this author
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Journal:
Antimicrobial agents and chemotherapy
Volume:
51
Issue:
12
Pages:
4315-4323
Publication date:
2007-12-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:ef52bafe-3c06-408c-a013-c9a23ff5d20c
Source identifiers:
30442
Local pid:
pubs:30442

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