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A perturbation in glutathione biosynthesis disrupts endoplasmic reticulum morphology and secretory membrane traffic in Arabidopsis thaliana.

Abstract:

To identify potentially novel and essential components of plant membrane trafficking mechanisms we performed a GFP-based forward genetic screen for seedling-lethal biosynthetic membrane trafficking mutants in Arabidopsis thaliana. Amongst these mutants, four recessive alleles of GSH2, which encodes glutathione synthase (GSH2), were recovered. Each allele was characterized by loss of the typical polygonal endoplasmic reticulum (ER) network and the accumulation of swollen ER-derived bodies whic...

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Publication status:
Published

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Journal:
Plant journal : for cell and molecular biology
Volume:
71
Issue:
6
Pages:
881-894
Publication date:
2012-09-01
DOI:
EISSN:
1365-313X
ISSN:
0960-7412
Source identifiers:
312246

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