Journal article
Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis.
- Abstract:
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An adequate supply of oxygen and nutrients is essential for survival and metabolism of cells, and consequentially for normal homeostasis. Alterations in tissue oxygen tension have been postulated to contribute to a number of pathologies, including rheumatoid arthritis (RA), in which the characteristic synovial expansion is thought to outstrip the oxygen supply, leading to areas of synovial hypoxia and hypoperfusion. Indeed, the idea of a therapeutic modality aimed at 'starving' tissue of bloo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 547.4KB, Terms of use)
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- Publisher copy:
- 10.1186/ar2568
Authors
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- Arthritis research and therapy More from this journal
- Volume:
- 11
- Issue:
- 1
- Pages:
- 201
- Publication date:
- 2009-01-01
- DOI:
- EISSN:
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1478-6362
- ISSN:
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1478-6354
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:230550
- UUID:
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uuid:ef39fdcd-fe44-4aea-94bc-1adb2921b73d
- Local pid:
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pubs:230550
- Source identifiers:
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230550
- Deposit date:
-
2013-11-16
Terms of use
- Copyright holder:
- BioMed Central Ltd
- Copyright date:
- 2009
- Notes:
- This article is licenced under a Creative Commons Attribution License.
- Licence:
- CC Attribution (CC BY)
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