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Mimics of L-rhamnose: Analogues of rhamnopyranose containing a constituent alpha-amino acid at the anomeric position. A rhamnopyranose analogue of hydantocidin

Abstract:
Ionic brominative oxidation of 2-amino derivatives of protected heptonolactones derived from L-rhamnose provides a key bicyclic intermediate for the synthesis of analogues of L-rhamnopyranose with spirohydantoins and spirodiketopiperazines at the anomeric position; the same intermediate can be used for the synthesis of novel glycopeptides containing a constituent rhamnopyranose amino acid. such materials may allow an approach to new studies of diseases induced by mycobacteria, such as tuberculosis and leprosy.
Publication status:
Published

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Publisher copy:
10.1016/0957-4166(96)00014-6

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
TETRAHEDRON-ASYMMETRY More from this journal
Volume:
7
Issue:
2
Pages:
391-394
Publication date:
1996-02-01
DOI:
ISSN:
0957-4166


Pubs id:
pubs:45086
UUID:
uuid:ef396526-8991-4db0-b69c-2a90826b2ce1
Local pid:
pubs:45086
Source identifiers:
45086
Deposit date:
2012-12-19
ARK identifier:

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