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Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride

Abstract:

Herein, we report the radiosynthesis of 18F-difluoromethylarenes via the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [18F]fluoride.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/c8sc05096a

Authors


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Role:
Author
ORCID:
0000-0003-1843-2189
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Role:
Author
ORCID:
0000-0003-0293-1530


Publisher:
Royal Society of Chemistry
Journal:
Chemical Science More from this journal
Volume:
10
Issue:
11
Pages:
3237-3241
Publication date:
2019-01-29
Acceptance date:
2019-01-28
DOI:
EISSN:
2041-6539
ISSN:
2041-6520


Language:
English
Keywords:
Pubs id:
pubs:972553
UUID:
uuid:ef33137e-73ab-49f9-8eeb-26880d0a170e
Local pid:
pubs:972553
Source identifiers:
972553
Deposit date:
2019-02-13

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