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Connectivity of the pedunculopontine nucleus in parkinsonian freezing of gait.

Abstract:

Parkinson's disease (PD) may involve sudden unintended arrests in gait or failure to initiate gait, known as gait freezing. Deep brain stimulation of the pedunculopontine nucleus (PPN) has been found to be an effective therapy for this phenomenon. In this study, we characterized the connectivity of the PPN freezing of gait (FOG) patients, compared with non-FOG PD and healthy controls using diffusion tensor imaging techniques. Differences in PPN connectivity profiles of the study groups were s...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
Neuroreport
Volume:
21
Issue:
14
Pages:
914-916
Publication date:
2010-10-05
DOI:
EISSN:
1473-558X
ISSN:
0959-4965
URN:
uuid:ef1087d6-2d76-44fe-9f3a-49b73d3e08cd
Source identifiers:
140892
Local pid:
pubs:140892

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