Malaria vaccines: the stage we are at.

Journal article

With over 1 million deaths annually attributed to malaria, an effective vaccine is an urgently needed intervention. However, the various stages of the malaria parasite lifecycle have differing protective immune mechanisms and clinical endpoints, and usually different, often polymorphic, antigens. Trials using an increasing variety of vaccine platforms and antigens are under way in an attempt to achieve this long-awaited goal.

Authors: Todryk, S; Hill, A

• Publication status: Published
• Journal: Nature reviews. Microbiology
• Volume: 5
• Issue: 7
• Pages: 487-489
• Publication date: 2007-07-01
• DOI: 10.1038/nrmicro1712
• EISSN: 1740-1534
• ISSN: 1740-1526
• Language: English
• Keywords: Clinical Trials as Topic; Humans; Animals; Erythrocytes; Antigens, Protozoan; Plasmodium falciparum; Malaria Vaccines; Life Cycle Stages; Malaria, Falciparum