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A Bayesian approach to sequential meta-analysis

Abstract:

As evidence accumulates within a meta-analysis, it is desirable to determine when the results could be considered conclusive to guide systematic review updates and future trial designs. Adapting sequential testing methodology from clinical trials for application to pooled meta-analytic effect size estimates appears well suited for this objective. In this paper we describe a Bayesian sequential meta-analysis method, in which an informative heterogeneity prior is employed and stopping rule crit...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/sim.7052

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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
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Grant:
Research Methods Fellowship (NIHR-RMFI- 2015-05-015
Publisher:
John Wiley and Sons, Ltd
Journal:
Statistics in Medicine More from this journal
Volume:
35
Issue:
29
Pages:
5356–5375
Publication date:
2016-01-01
Acceptance date:
2016-07-01
DOI:
ISSN:
1097-0258
Keywords:
Pubs id:
pubs:631423
UUID:
uuid:ef0143ad-7f53-483c-a99f-2ffcbc054b76
Local pid:
pubs:631423
Source identifiers:
631423
Deposit date:
2016-07-01

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