Impact of perioperative bleeding on the protective effect of β-blockers during infrarenal aortic reconstruction.

Journal article

BACKGROUND: The use of β-blockers during the perioperative period remains controversial. Although some studies have demonstrated their protective effects regarding postoperative cardiac complications, others have demonstrated increased mortality when β-blockers were introduced before surgery. METHODS: In this observational study involving 1,801 patients undergoing aortic reconstruction, we prospectively assessed β-blocker therapy compared with no β-blocker therapy, with regard to cardiac and...

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Authors: Le Manach, Y; Collins, G; Ibanez, C; Goarin, J; Coriat, P

• Publication status: Published
• Journal: Anesthesiology
• Volume: 117
• Issue: 6
• Pages: 1203-1211
• Publication date: 2012-12-01
• DOI: 10.1097/aln.0b013e31825adaea
• EISSN: 1528-1175
• ISSN: 0003-3022
• Language: English
• Keywords: Percutaneous Coronary Intervention; Hospital Mortality; Treatment Outcome; Aged; Aorta, Abdominal; Adrenergic beta-Antagonists; Female; Male; Perioperative Care; Acute Kidney Injury; Humans; Blood Loss, Surgical; Prospective Studies; Middle Aged; Cardiovascular Diseases