Journal article
Enzyme kinetics at high enzyme concentration.
- Abstract:
-
We re-visit previous analyses of the classical Michaelis-Menten substrate-enzyme reaction and, with the aid of the reverse quasi-steady-state assumption, we challenge the approximation d[C]/dt approximately 0 for the basic enzyme reaction at high enzyme concentration. For the first time, an approximate solution for the concentrations of the reactants uniformly valid in time is reported. Numerical simulations are presented to verify this solution. We show that an analytical approximation can b...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Bulletin of mathematical biology
- Volume:
- 62
- Issue:
- 3
- Pages:
- 483-499
- Publication date:
- 2000-05-01
- DOI:
- EISSN:
-
1522-9602
- ISSN:
-
0092-8240
- Source identifiers:
-
25479
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:25479
- UUID:
-
uuid:eef0ecf6-b0ee-4d24-9d7c-b9742f37ea87
- Local pid:
- pubs:25479
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
If you are the owner of this record, you can report an update to it here: Report update to this record