Control of Drosophila eye specification by Wingless signalling.

Journal article

Organ formation requires early specification of the groups of cells that will give rise to specific structures. The Wingless protein plays an important part in this regional specification of imaginal structures in Drosophila, including defining the region of the eye-antennal disc that will become retina. We show that Wingless signalling establishes the border between the retina and adjacent head structures by inhibiting the expression of the eye specification genes eyes absent, sine oculis an...

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Authors: Baonza, A; Freeman, M

• Publication status: Published
• Journal: Development (Cambridge, England)
• Volume: 129
• Issue: 23
• Pages: 5313-5322
• Publication date: 2002-12-01
• DOI: 10.1242/dev.00096
• EISSN: 1477-9129
• ISSN: 0950-1991
• Language: English
• Keywords: Wnt1 Protein; Female; Axin Protein; Drosophila melanogaster; Nuclear Proteins; Recombinant Fusion Proteins; Proto-Oncogene Proteins; Gene Expression Regulation, Developmental; Drosophila Proteins; Flow Cytometry; Eye Proteins; Homeodomain Proteins; Trans-Activators; Transcription Factors; Carrier Proteins; Adaptor Proteins, Signal Transducing; Armadillo Domain Proteins; Repressor Proteins; Genes, Insect; Cell Separation; Genes, Reporter; Body Patterning; Signal Transduction; Photoreceptor Cells, Invertebrate; Genes, Homeobox; Male; Animals