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The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership.

Abstract:

BACKGROUND: Artemisinin-based combination therapy is currently recommended worldwide for the treatment of uncomplicated malaria. Fixed-dose combinations are preferred as they favour compliance. This paper reports on the initial phases of the pharmaceutical development of an artesunate-amodiaquine (ASAQ) bilayer co-formulation tablet, undertaken following pre-formulation studies by a network of scientists and industrials from institutions of both industrialized and low income countries. METHOD...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1475-2875-10-142

Authors


Kiechel, JR More by this author
Caminiti, A More by this author
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Conseil Régional d'Aquitaine More from this funder
Incubateur Régional d'Aquitaine More from this funder
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
Malaria Journal Journal website
Volume:
10
Issue:
1
Pages:
Article: 142
Publication date:
2011
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:eec876f7-eff3-4dee-9444-fb52858baf06
Source identifiers:
166521
Local pid:
pubs:166521

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