Journal article
Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis
- Abstract:
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Background Rare genetic variants cause pulmonary arterial hypertension, but the contribution of common genetic variation to disease risk and natural history is poorly characterised. We tested for genome-wide association for pulmonary arterial hypertension in large international cohorts and assessed the contribution of associated regions to outcomes.
Methods We did two separate genome-wide association studies (GWAS) and a meta-analysis of pulmonary a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 1.2MB, Terms of use)
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- Publisher copy:
- 10.1016/S2213-2600(18)30409-0
Authors
+ National Center for Advancing Translational Sciences, National Institutes of Health
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- Grant:
- UL1 TR002243
+ National Center for Research Resources, National Institutes of Health
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- Grant:
- S10 RR025141
- Publisher:
- Elsevier
- Journal:
- Lancet Respiratory Medicine More from this journal
- Volume:
- 7
- Issue:
- 3
- Pages:
- 227-238
- Publication date:
- 2018-12-05
- Acceptance date:
- 2018-09-26
- DOI:
- EISSN:
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2213-2619
- ISSN:
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2213-2600
- Pmid:
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30527956
- Language:
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English
- Keywords:
- Pubs id:
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pubs:980904
- UUID:
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uuid:eeb6e488-b7f8-45d7-a21b-4e73d0436ef1
- Local pid:
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pubs:980904
- Source identifiers:
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980904
- Deposit date:
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2019-04-11
Terms of use
- Copyright holder:
- Rhodes et al
- Copyright date:
- 2018
- Notes:
- © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
- Licence:
- CC Attribution (CC BY)
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