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Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.

Abstract:

The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamics, with practical applications to malaria control. The ability to identify the geographic origin and trace the migratory patterns of parasites with clinically important phenotypes such as drug resistance is particularly relevant. With increasing single-nucleotide polymorphism (SNP) discovery from ongoing Plasmodium genome sequencing projects, a demand for high SNP and sample throughput genotypi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0020251

Authors


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Bill and Melinda Gates Foundation More from this funder
Wellcome Trust More from this funder
Medical Research Council More from this funder
Division of Intramural Research of the National Institutes of Health and National Institute of Allergy and Infectious Diseases More from this funder
National Health and Medical Research Council Australia More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
6
Issue:
6
Pages:
Article: e20251
Publication date:
2011-01-05
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:eea1d81d-fc21-433e-a4a7-bd687547f6f6
Source identifiers:
154825
Local pid:
pubs:154825

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