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Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.

Abstract:

The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamics, with practical applications to malaria control. The ability to identify the geographic origin and trace the migratory patterns of parasites with clinically important phenotypes such as drug resistance is particularly relevant. With increasing single-nucleotide polymorphism (SNP) discovery from ongoing Plasmodium genome sequencing projects, a demand for high SNP and sample throughput genotypi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1371/journal.pone.0020251

Authors


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National Budget of the Institut de Recherche en Sciences de le Sante-Burkina Faso More from this funder
National Health and Medical Research Council Australia More from this funder
National Malaria Control Program More from this funder
European and Developing Countries Clinical Trial Partnership More from this funder
Howard Hughes Medical Institution More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
6
Issue:
6
Article number:
e20251
Publication date:
2011-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Source identifiers:
154825
Language:
English
Keywords:
UUID:
uuid:eea1d81d-fc21-433e-a4a7-bd687547f6f6
Local pid:
pubs:154825
Deposit date:
2012-12-19

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