Journal article icon

Journal article

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria.

Abstract:

There is growing epidemiological and molecular evidence that ABO blood group affects host susceptibility to severe Plasmodium falciparum infection. The high frequency of common ABO alleles means that even modest differences in susceptibility could have a significant impact on the health of people living in malaria endemic regions. We performed an association study, the first to utilize key molecular genetic variation underlying the ABO system, genotyping >9000 individuals across three Afri...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/hmg/ddm331

Authors


Griffiths, MJ More by this author
Diakite, M More by this author
Forton, JT More by this author
Expand authors...
Journal:
Hum Mol Genet
Volume:
17
Issue:
4
Pages:
567-576
Publication date:
2008-02-15
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:ee8956a6-62bd-4f64-89f0-e492e25314d3
Source identifiers:
34047
Local pid:
pubs:34047

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP