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Lactate acquisition promotes successful colonization of the murine genital tract by Neisseria gonorrhoeae.

Abstract:

Previous studies on Neisseria gonorrhoeae have demonstrated that metabolism of lactate in the presence of glucose increases the growth rate of the bacterium and enhances its resistance to complement-mediated killing. Although these findings in vitro suggest that the acquisition of lactate promotes gonococcal colonization, the significance of this carbon source to the survival of the gonococcus in vivo remains unknown. To investigate the importance of lactate utilization during Neisseria gonor...

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Publisher copy:
10.1128/iai.01530-06

Authors


Schneider, MC More by this author
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Journal:
Infection and immunity
Volume:
75
Issue:
3
Pages:
1318-1324
Publication date:
2007-03-05
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:ee6d98a4-fc06-49f1-8bc8-f88e163b1f06
Source identifiers:
249490
Local pid:
pubs:249490

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