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Atovaquone/proguanil therapy for Plasmodium falciparum and Plasmodium vivax malaria in Indonesians who lack clinical immunity.

Abstract:
Thirty-eight of 295 subjects participating in a randomized, double-blind, placebo-controlled trial of the efficacy of daily administration of atovaquone/proguanil for malaria prevention developed malaria at some time during the 20-week prophylaxis period. These subjects (3 atovaquone/proguanil recipients and 35 placebo recipients) were treated with 4 tablets of atovaquone/proguanil per day for 3 days. Atovaquone/proguanil provided safe, well-tolerated, and effective therapy for uncomplicated malaria in nonimmune Indonesians.
Publication status:
Published

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Publisher copy:
10.1086/343750

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Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:
35
Issue:
9
Pages:
e92-e95
Publication date:
2002-11-01
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Source identifiers:
81574

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