Journal article

DNA methylation and Rett syndrome

Abstract:: Methylation of cytosine in human DNA has been studied for over 60 years, but has only recently been confirmed as an important player in human disease. Rett syndrome is a neurological disorder caused by mutations in the MeCP2 protein, which has been shown to bind methylated DNA and repress transcription. This review will focus on experiments addressing the basic properties of MeCP2 and on mouse models of Rett syndrome that are starting to yield insights into this condition.

Publication status:: Published

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APA Style

Kriaucionis, S., & Bird, A. (2003). DNA methylation and Rett syndrome. HUMAN MOLECULAR GENETICS, 12(REV. ISS. 2), R221–R227.

MLA Style

Kriaucionis, S, and A Bird. “DNA Methylation and Rett Syndrome.” HUMAN MOLECULAR GENETICS, vol. 12, no. REV. ISS. 2, 2003, pp. R221–R227.

Chicago Style

Kriaucionis, S, and A Bird. 2003. “DNA Methylation and Rett Syndrome.” HUMAN MOLECULAR GENETICS 12 (REV. ISS. 2): R221–R227.
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Publisher copy:: 10.1093/hmg/ddg2863

Authors

+ Kriaucionis, S More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

+ Bird, A More by this author

Role:: Author

Journal:: HUMAN MOLECULAR GENETICS More from this journal
Volume:: 12
Issue:: REV. ISS. 2
Pages:: R221-R227
Publication date:: 2003-10-15
DOI:: 10.1093/hmg/ddg2863
ISSN:: 0964-6906

Pubs id:: pubs:90269
UUID:: uuid:ee595ffe-5f12-46a0-8860-df527726aa0b
Local pid:: pubs:90269
Source identifiers:: 90269
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_ee595ffe5f1246a08860df527726aa0b

Terms of use

Copyright date:: 2003

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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