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Journal article

Effects of monoclonal antibodies to the alpha and beta chains of the human lymphocyte function-associated (H-LFA-1) antigen on T lymphocyte functions.

Abstract:

The ability of two antibodies, one specific for the alpha chain, p180, and the other for the beta chain, p95, of the human lymphocyte function-associated (LFA-1) antigens, to inhibit T cell function was measured. Both antibodies inhibited T cell-mediated lysis of virus-infected target cells and of K562 cells. Only the anti-beta chain antibody inhibited natural killer cell lysis of K562. The antibodies inhibited cytotoxic T lymphocyte cell (CTL) lysis of HLA-mismatched target cells in the pres...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830150905

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
European journal of immunology
Volume:
15
Issue:
9
Pages:
888-892
Publication date:
1985-09-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:ee2a69fb-a7bd-45e9-8d5e-e4a41d2155ae
Source identifiers:
42483
Local pid:
pubs:42483

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