Journal article icon

Journal article

Accessory factors determine the order of strand exchange in Xer recombination at psi.

Abstract:

Xer site-specific recombination in Escherichia coli converts plasmid multimers to monomers, thereby ensuring their correct segregation at cell division. Xer recombination at the psi site of plasmid pSC101 is preferentially intramolecular, giving products of a single topology. This intramolecular selectivity is imposed by accessory proteins, which bind at psi accessory sequences and activate Xer recombination at the psi core. Strand exchange proceeds sequentially within the psi core; XerC firs...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/emboj/cdf379

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
The EMBO journal
Volume:
21
Issue:
14
Pages:
3888-3897
Publication date:
2002-07-05
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:ee272af0-26f4-4667-bbf4-1611a213a58b
Source identifiers:
99936
Local pid:
pubs:99936

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP