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Journal article

Accessory factors determine the order of strand exchange in Xer recombination at psi.

Abstract:

Xer site-specific recombination in Escherichia coli converts plasmid multimers to monomers, thereby ensuring their correct segregation at cell division. Xer recombination at the psi site of plasmid pSC101 is preferentially intramolecular, giving products of a single topology. This intramolecular selectivity is imposed by accessory proteins, which bind at psi accessory sequences and activate Xer recombination at the psi core. Strand exchange proceeds sequentially within the psi core; XerC firs...

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Publication status:
Published

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Publisher copy:
10.1093/emboj/cdf379

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
EMBO journal
Volume:
21
Issue:
14
Pages:
3888-3897
Publication date:
2002-07-01
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
Source identifiers:
99936
Language:
English
Keywords:
Pubs id:
pubs:99936
UUID:
uuid:ee272af0-26f4-4667-bbf4-1611a213a58b
Local pid:
pubs:99936
Deposit date:
2012-12-19

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