Short report: in vivo sensitivity of Plasmodium falciparum to halofantrine in southern central Vietnam.

Journal article

Drug-resistant Plasmodium falciparum is present in Vietnam. We assessed the in vivo sensitivity of P. falciparum to halofantrine in two villages in the southern part of central Vietnam. Halofantrine (8 mg/kg x 3 doses) was administered to 37 patients with either P. falciparum (n = 32) or mixed P. falciparum/P. vivax malaria (n = 5). End points were parasite sensitivity or resistance (RI/RII/RIII) determined by parasite clearance, persistence, or recurrence during 28 days of follow-up. By day ...

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Authors: Doan, H; Taylor, W; Nguyen, D; Tran, T; Fryauff, D

• Publication status: Published
• Journal: American journal of tropical medicine and hygiene
• Volume: 69
• Issue: 5
• Pages: 553-554
• Publication date: 2003-11-01
• EISSN: 1476-1645
• ISSN: 0002-9637
• Language: English
• Keywords: Adolescent; Male; Antimalarials; Vietnam; Child; Drug Resistance; Child, Preschool; Plasmodium falciparum; Recurrence; Female; Humans; Adult; Parasitic Sensitivity Tests; Malaria, Falciparum; Phenanthrenes; Animals