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The bone marrow in human cerebral malaria: parasite sequestration within sinusoids.

Abstract:

Bone marrow aspirates from patients with cerebral malaria were studied with the light and electron microscopes. Various abnormalities were found including: (1) an increase in plasma cells and macrophages, sometimes to a marked degree; (2) phagocytosis of parasitized red cells by macrophages and of merozoites by neutrophil metamyelocytes, neutrophil granulocytes and macrophages; (3) an increase in the proportion of eosinophil granulocytes and their precursors; (4) the presence of giant metamye...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
Journal:
British journal of haematology
Volume:
66
Issue:
3
Pages:
295-306
Publication date:
1987-07-05
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
URN:
uuid:edf1aa46-1ab1-4f88-8fbc-54ad22f3c814
Source identifiers:
507
Local pid:
pubs:507

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