- Abstract:
-
BACKGROUND: Impaired vitamin B(12) function and decreased vitamin B(12) status have been associated with neurological and cognitive impairment. Current assays analyze total vitamin B(12) concentration, only a small percentage of which is metabolically active. Concentrations of this active component, carried on holotranscobalamin (holoTC), may be of greater relevance than total vitamin B(12). METHODS: We compared the utility of serum holoTC with conventional vitamin B(12) for detection of vita...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1373/clinchem.2006.080382
-
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- Journal:
- Clinical chemistry
- Volume:
- 53
- Issue:
- 5
- Pages:
- 963-970
- Publication date:
- 2007-05-05
- DOI:
- EISSN:
-
1530-8561
- ISSN:
-
0009-9147
- URN:
-
uuid:edee9230-e3a8-432f-90c7-c6fa802c618a
- Source identifiers:
-
49245
- Local pid:
- pubs:49245
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin.
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