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Conjugate addition of nitrogen nucleophiles to an alpha,beta-unsaturated pyrrolidinone

Abstract:
The conjugate addition of nitrogen nucleophiles to α,β-unsaturated lactam 1b under very mild conditions occurs in good yield with high diastereoselectivity. Deprotection provides a simple access to β-aminopyrrolidinones in excellent overall yield.
Publication status:
Published

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Publisher copy:
10.1016/S0040-4039(97)01312-9

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
TETRAHEDRON LETTERS More from this journal
Volume:
38
Issue:
33
Pages:
5891-5894
Publication date:
1997-08-18
DOI:
ISSN:
0040-4039


Language:
English
Pubs id:
pubs:45687
UUID:
uuid:edcbbd88-de64-4338-8fa6-8cda8de23288
Local pid:
pubs:45687
Source identifiers:
45687
Deposit date:
2012-12-19
ARK identifier:

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