Neuroanatomy of impaired self-awareness in Alzheimer's disease and mild cognitive impairment.

Journal article

INTRODUCTION: Patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) may be unaware of their cognitive impairment. The neuroanatomical mechanisms underlying this symptom, termed anosognosia or impaired self-awareness, are still poorly understood. In the present study we aimed to explore the functional correlates of self-awareness in patients with MCI and AD. METHODS: Fifty-one participants (17 healthy elderly, 17 patients with MCI, and 17 patients with AD), each accompanie...

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Authors: Zamboni, G; Drazich, E; McCulloch, E; Filippini, N; Mackay, C

• Publication status: Published
• Journal: Cortex; a journal devoted to the study of the nervous system and behavior
• Volume: 49
• Issue: 3
• Pages: 668-678
• Publication date: 2013-03-01
• DOI: 10.1016/j.cortex.2012.04.011
• EISSN: 1973-8102
• ISSN: 0010-9452
• Language: English
• Keywords: Functional Neuroimaging; Self Concept; Aged; Magnetic Resonance Imaging; Alzheimer Disease; Aged, 80 and over; Neuropsychological Tests; Brain Mapping; Female; Reaction Time; Mild Cognitive Impairment; Brain; Humans; Image Processing, Computer-Assisted; Male; Awareness