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The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation

Abstract:
Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus providing a basis for novel systems for biological clean-up of these inert compounds.
Publication status:
Published

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Publisher copy:
10.1039/a909536e

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author


Journal:
CHEMICAL COMMUNICATIONS More from this journal
Issue:
3
Pages:
247-248
Publication date:
2000-01-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345


Language:
English
Pubs id:
pubs:37258
UUID:
uuid:edb48e3c-8c5b-4f6b-a844-5da2c7a28c5c
Local pid:
pubs:37258
Source identifiers:
37258
Deposit date:
2012-12-19
ARK identifier:

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