Acoustic, mechanical and near-infrared profiling of osteoarthritic progression in bovine joints.

Journal article

Early-stage treatments for osteoarthritis are attracting considerable interest as a means to delay, or avoid altogether, the pain and lack of mobility associated with late-stage disease, and the considerable burden that it places on the community. With the development of these treatments comes a need to assess the tissue to which they are applied, both in trialling of new treatments and as an aid to clinical decision making. Here, we measure a range of mechanical indentation, ultrasound and n...

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Authors: Brown, C; Oloyede, A; Crawford, R; Thomas, G; Price, A

• Publication status: Published
• Journal: Physics in medicine and biology
• Volume: 57
• Issue: 2
• Pages: 547-559
• Publication date: 2012-01-01
• DOI: 10.1088/0031-9155/57/2/547
• EISSN: 1361-6560
• ISSN: 0031-9155
• Language: English
• Keywords: Joints; Mechanical Processes; Osteoarthritis; Animals; Collagen; Disease Progression; Proteoglycans; Biomechanical Phenomena; Materials Testing; Cattle; Spectrophotometry, Infrared