Tissue repair and the dynamics of the extracellular matrix.

Journal article

Abstract:: Repair of tissue after injury depends on the synthesis of a fibrous extracellular matrix to replace lost or damaged tissue. Newly deposited extracellular matrix is then re-modeled over time to emulate normal tissue. The extracellular matrix directs repair by regulating the behavior of the wide variety of cell types that are mobilized to the damaged area in order to rebuild the tissue. Acute inflammation, re-epithelialization, and contraction all depend on cell-extracellular matrix interaction...
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Institution:

University of Oxford

Division:

MSD

Department:

NDORMS

Role:

Author

Role:

Author

Role:

Author

Journal:: international journal of biochemistry and cell biology More from this journal
Volume:: 36
Issue:: 6
Pages:: 1031-1037
Publication date:: 2004-06-01
DOI:: 10.1016/j.biocel.2003.12.003
EISSN:: 1878-5875
ISSN:: 1357-2725

Language:: English
Keywords:: Osteopontin

Skin

Wound Healing

Animals

Extracellular Matrix

Sialoglycoproteins

Mice

Humans

Extracellular Matrix Proteins
Pubs id:: pubs:225563
UUID:: uuid:ed88bed4-9e44-4ee0-8b8b-1ea99781df1e
Local pid:: pubs:225563
Source identifiers:: 225563
Deposit date:: 2013-11-16

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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