Journal article
Interleukin 13-mediated colitis in the absence of IL-4Rα signalling.
- Abstract:
-
Sufficient evidence points to interleukin 13 (IL-13) as an important pathological factor in UC and raises hopes to a promising new treatment strategy.1–3 However, the outcomes of two recent clinical trials, both published in Gut 2015, suggest otherwise.4 ,5 A commentary published in the same issue described these results as crushing the enthusiasm for anti-IL-13 treatment in UC.6 In this letter, we show evidence that the disease outcome is determined by the type of signalling pathway used by ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Gastroenterology Foundation of South Africa
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South African Research Chair Initiative
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National Research Foundation
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Carnegie Corporation
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Bibliographic Details
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- Gut Journal website
- Publication date:
- 2017-02-01
- Acceptance date:
- 2017-02-05
- DOI:
- ISSN:
-
0017-5749 and 1468-3288
- Source identifiers:
-
683980
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:683980
- UUID:
-
uuid:ed81cd46-8a0d-4691-8917-863139212e79
- Local pid:
- pubs:683980
- Deposit date:
- 2017-05-05
Terms of use
- Copyright holder:
- BMJ Publishing Group Ltd and British Society of Gastroenterology
- Copyright date:
- 2017
- Notes:
- © 2017 BMJ Publishing Group Ltd and British Society of Gastroenterology. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
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